T4I (p.Thr4Ile) variant of CASP3 (Caspase-3)
T4I (p.Thr4Ile) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data and structural context.
T4I (p.Thr4Ile) variant details
- p.Thr4Ile
- gnomAD rs1472060631
- Missense
- Variant Prioritization Score for Impact Estimate 0.135
- REVEL 0.17
- CADD 5.18
- PolyPhen-2 0.10
- SIFT 0.08
- Most common in the African/African-American population (allele frequency 0.00031)
- Structural context available