T4A (p.Thr4Ala) variant of CASP3 (Caspase-3)
T4A (p.Thr4Ala) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
T4A (p.Thr4Ala) variant details
- p.Thr4Ala
- TOPMed rs1459765876
- Missense
- Variant Prioritization Score for Impact Estimate 0.123
- REVEL 0.10
- CADD 12.50
- PolyPhen-2 0.01
- SIFT 0.32
- Population evidence available
- Structural context available