S63F (p.Ser63Phe) variant of CASP3 (Caspase-3)
S63F (p.Ser63Phe) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
S63F (p.Ser63Phe) variant details
- p.Ser63Phe
- cosmic curated COSV57724
- Ensembl rs762383029
- Missense
- Variant Prioritization Score for Impact Estimate 0.131
- REVEL 0.07
- CADD 14.30
- PolyPhen-2 0.01
- SIFT 0.39
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available