S58N (p.Ser58Asn) variant of CASP3 (Caspase-3)
S58N (p.Ser58Asn) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
S58N (p.Ser58Asn) variant details
- p.Ser58Asn
- ExAC rs780844343
- TOPMed rs780844343
- gnomAD rs780844343
- Missense
- Variant Prioritization Score for Impact Estimate 0.226
- REVEL 0.04
- CADD 6.41
- PolyPhen-2 0.01
- SIFT 0.48
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available