S112R (p.Ser112Arg) variant of CASP3 (Caspase-3)
S112R (p.Ser112Arg) in CASP3 (Caspase-3) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
S112R (p.Ser112Arg) variant details
- p.Ser112Arg
- gnomAD 4-184631911-TG-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.659
- CADD 30.00
- Population evidence available
- Structural context available
- Literature evidence available