R93L (p.Arg93Leu) variant of CASP3 (Caspase-3)
R93L (p.Arg93Leu) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
R93L (p.Arg93Leu) variant details
- p.Arg93Leu
- gnomAD rs1185617085
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.10
- CADD 17.70
- PolyPhen-2 0.12
- SIFT 0.13
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available