R93H (p.Arg93His) variant of CASP3 (Caspase-3)
R93H (p.Arg93His) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
R93H (p.Arg93His) variant details
- p.Arg93His
- cosmic curated COSV57724
- gnomAD rs1185617085
- Missense
- Variant Prioritization Score for Impact Estimate 0.25
- REVEL 0.09
- CADD 17.20
- PolyPhen-2 0.01
- SIFT 0.20
- Most common in the HGDP:BURUSHO population (allele frequency 0.042)
- Structural context available