R93C (p.Arg93Cys) variant of CASP3 (Caspase-3)
R93C (p.Arg93Cys) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
R93C (p.Arg93Cys) variant details
- p.Arg93Cys
- cosmic curated COSV57725
- TOPMed rs1258017334
- gnomAD rs1258017334
- Missense
- Variant Prioritization Score for Impact Estimate 0.0915
- REVEL 0.10
- CADD 0.23
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available