R75K (p.Arg75Lys) variant of CASP3 (Caspase-3)
R75K (p.Arg75Lys) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
R75K (p.Arg75Lys) variant details
- p.Arg75Lys
- gnomAD 4-184632351-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.211
- REVEL 0.05
- CADD 17.00
- PolyPhen-2 0.10
- SIFT 0.29
- Population evidence available
- Structural context available
- Literature evidence available