R64W (p.Arg64Trp) variant of CASP3 (Caspase-3)
R64W (p.Arg64Trp) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.54 / 1. The record also includes population frequency data and structural context.
R64W (p.Arg64Trp) variant details
- p.Arg64Trp
- ExAC rs769869735
- TOPMed rs769869735
- gnomAD rs769869735
- Missense
- Variant Prioritization Score for Impact Estimate 0.539
- REVEL 0.49
- CADD 32.00
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available