P18T (p.Pro18Thr) variant of CASP3 (Caspase-3)
P18T (p.Pro18Thr) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
P18T (p.Pro18Thr) variant details
- p.Pro18Thr
- ExAC rs755080452
- TOPMed rs755080452
- gnomAD rs755080452
- Missense
- Variant Prioritization Score for Impact Estimate 0.0482
- REVEL 0.03
- CADD 0.18
- PolyPhen-2 0.00
- SIFT 0.65
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available