P18S (p.Pro18Ser) variant of CASP3 (Caspase-3)
P18S (p.Pro18Ser) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.06 / 1. The record also includes population frequency data and structural context.
P18S (p.Pro18Ser) variant details
- p.Pro18Ser
- cosmic curated COSV57725
- ExAC rs755080452
- TOPMed rs755080452
- gnomAD rs755080452
- Missense
- Variant Prioritization Score for Impact Estimate 0.0612
- REVEL 0.05
- CADD 0.13
- PolyPhen-2 0.00
- SIFT 0.77
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available