P18L (p.Pro18Leu) variant of CASP3 (Caspase-3)
P18L (p.Pro18Leu) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.05 / 1. The record also includes population frequency data and structural context.
P18L (p.Pro18Leu) variant details
- p.Pro18Leu
- cosmic curated COSV57724
- ExAC rs747108081
- TOPMed rs747108081
- gnomAD rs747108081
- Missense
- Variant Prioritization Score for Impact Estimate 0.0482
- REVEL 0.03
- CADD 1.42
- PolyPhen-2 0.00
- SIFT 0.38
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available