L99F (p.Leu99Phe) variant of CASP3 (Caspase-3)
L99F (p.Leu99Phe) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
L99F (p.Leu99Phe) variant details
- p.Leu99Phe
- gnomAD 4-184632278-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.245
- REVEL 0.15
- CADD 11.10
- PolyPhen-2 0.98
- SIFT 0.06
- Population evidence available
- Structural context available
- Literature evidence available