L119P (p.Leu119Pro) variant of CASP3 (Caspase-3)
L119P (p.Leu119Pro) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.72 / 1. The record also includes population frequency data, published literature, and structural context.
L119P (p.Leu119Pro) variant details
- p.Leu119Pro
- gnomAD 4-184631892-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.722
- REVEL 0.78
- CADD 28.30
- PolyPhen-2 0.65
- SIFT 0.02
- Population evidence available
- Structural context available
- Literature evidence available