L118F (p.Leu118Phe) variant of CASP3 (Caspase-3)
L118F (p.Leu118Phe) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
L118F (p.Leu118Phe) variant details
- p.Leu118Phe
- ExAC rs754299277
- TOPMed rs754299277
- gnomAD rs754299277
- Missense
- Variant Prioritization Score for Impact Estimate 0.206
- REVEL 0.05
- CADD 12.10
- PolyPhen-2 0.17
- SIFT 0.15
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available