K53N (p.Lys53Asn) variant of CASP3 (Caspase-3)
K53N (p.Lys53Asn) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
K53N (p.Lys53Asn) variant details
- p.Lys53Asn
- TOPMed rs1742224066
- cosmic curated COSV57725
- Missense
- Variant Prioritization Score for Impact Estimate 0.315
- REVEL 0.27
- CADD 25.10
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the 1KG:MSL population (allele frequency 0.013)
- Structural context available