I48M (p.Ile48Met) variant of CASP3 (Caspase-3)
I48M (p.Ile48Met) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
I48M (p.Ile48Met) variant details
- p.Ile48Met
- TOPMed rs1742225815
- gnomAD rs1742225815
- Missense
- Variant Prioritization Score for Impact Estimate 0.213
- REVEL 0.14
- CADD 24.10
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available