I21L (p.Ile21Leu) variant of CASP3 (Caspase-3)
I21L (p.Ile21Leu) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
I21L (p.Ile21Leu) variant details
- p.Ile21Leu
- TOPMed rs1293102297
- gnomAD rs1293102297
- Missense
- Variant Prioritization Score for Impact Estimate 0.184
- REVEL 0.04
- CADD 9.14
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available