I20V (p.Ile20Val) variant of CASP3 (Caspase-3)
I20V (p.Ile20Val) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.10 / 1. The record also includes population frequency data and structural context.
I20V (p.Ile20Val) variant details
- p.Ile20Val
- cosmic curated COSV10815
- Missense
- Variant Prioritization Score for Impact Estimate 0.0953
- REVEL 0.05
- CADD 8.96
- PolyPhen-2 0.00
- SIFT 0.46
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available