I13V (p.Ile13Val) variant of CASP3 (Caspase-3)
I13V (p.Ile13Val) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
I13V (p.Ile13Val) variant details
- p.Ile13Val
- TOPMed rs1489468017
- gnomAD rs1489468017
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.04
- CADD 16.80
- PolyPhen-2 0.00
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 0.00041)
- Structural context available