I13S (p.Ile13Ser) variant of CASP3 (Caspase-3)
I13S (p.Ile13Ser) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
I13S (p.Ile13Ser) variant details
- p.Ile13Ser
- TOPMed rs201285392
- gnomAD rs201285392
- Missense
- Variant Prioritization Score for Impact Estimate 0.243
- REVEL 0.10
- CADD 22.80
- PolyPhen-2 0.00
- SIFT 0.10
- Most common in the HGDP:MAKRANI population (allele frequency 0.023)
- Structural context available