F78L (p.Phe78Leu) variant of CASP3 (Caspase-3)
F78L (p.Phe78Leu) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
F78L (p.Phe78Leu) variant details
- p.Phe78Leu
- 1000Genomes rs537053227
- ExAC rs537053227
- gnomAD rs537053227
- Missense
- Variant Prioritization Score for Impact Estimate 0.303
- REVEL 0.23
- CADD 23.50
- PolyPhen-2 0.95
- SIFT 0.06
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available