F114Y (p.Phe114Tyr) variant of CASP3 (Caspase-3)
F114Y (p.Phe114Tyr) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
F114Y (p.Phe114Tyr) variant details
- p.Phe114Tyr
- TOPMed rs1205494037
- gnomAD rs1205494037
- Missense
- Variant Prioritization Score for Impact Estimate 0.652
- REVEL 0.66
- CADD 27.50
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available