F114L (p.Phe114Leu) variant of CASP3 (Caspase-3)
F114L (p.Phe114Leu) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
F114L (p.Phe114Leu) variant details
- p.Phe114Leu
- TOPMed rs1742055681
- gnomAD rs1742055681
- Missense
- Variant Prioritization Score for Impact Estimate 0.406
- REVEL 0.33
- CADD 21.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available