E98K (p.Glu98Lys) variant of CASP3 (Caspase-3)
E98K (p.Glu98Lys) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
E98K (p.Glu98Lys) variant details
- p.Glu98Lys
- gnomAD 4-184632283-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- REVEL 0.05
- CADD 4.73
- PolyPhen-2 0.01
- SIFT 0.68
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available
- Literature evidence available