E95D (p.Glu95Asp) variant of CASP3 (Caspase-3)
E95D (p.Glu95Asp) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
E95D (p.Glu95Asp) variant details
- p.Glu95Asp
- gnomAD 4-184632290-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.138
- REVEL 0.07
- CADD 11.50
- PolyPhen-2 0.01
- SIFT 0.45
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available
- Literature evidence available