E76Q (p.Glu76Gln) variant of CASP3 (Caspase-3)
E76Q (p.Glu76Gln) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
E76Q (p.Glu76Gln) variant details
- p.Glu76Gln
- ExAC rs751157550
- TOPMed rs751157550
- gnomAD rs751157550
- Missense
- Variant Prioritization Score for Impact Estimate 0.239
- REVEL 0.06
- CADD 19.20
- PolyPhen-2 0.07
- SIFT 0.22
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00019)
- Structural context available