E106A (p.Glu106Ala) variant of CASP3 (Caspase-3)
E106A (p.Glu106Ala) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data, published literature, and structural context.
E106A (p.Glu106Ala) variant details
- p.Glu106Ala
- gnomAD 4-184631931-T-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.44
- REVEL 0.26
- CADD 32.00
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available
- Literature evidence available