D90H (p.Asp90His) variant of CASP3 (Caspase-3)
D90H (p.Asp90His) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
D90H (p.Asp90His) variant details
- p.Asp90His
- TOPMed rs1424266770
- gnomAD rs1424266770
- Missense
- Variant Prioritization Score for Impact Estimate 0.507
- REVEL 0.31
- CADD 24.70
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 8.8e-05)
- Structural context available