D70N (p.Asp70Asn) variant of CASP3 (Caspase-3)
D70N (p.Asp70Asn) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.
D70N (p.Asp70Asn) variant details
- p.Asp70Asn
- TOPMed rs1333458950
- gnomAD rs1333458950
- Missense
- Variant Prioritization Score for Impact Estimate 0.579
- REVEL 0.51
- CADD 25.80
- PolyPhen-2 0.45
- SIFT 0.01
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available