D68N (p.Asp68Asn) variant of CASP3 (Caspase-3)
D68N (p.Asp68Asn) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data and structural context.
D68N (p.Asp68Asn) variant details
- p.Asp68Asn
- TOPMed rs958101906
- gnomAD rs958101906
- Missense
- Variant Prioritization Score for Impact Estimate 0.528
- REVEL 0.33
- CADD 27.10
- PolyPhen-2 0.97
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available