D34A (p.Asp34Ala) variant of CASP3 (Caspase-3)
D34A (p.Asp34Ala) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
D34A (p.Asp34Ala) variant details
- p.Asp34Ala
- gnomAD rs1742229467
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- REVEL 0.15
- CADD 22.80
- PolyPhen-2 0.06
- SIFT 0.06
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available