D107H (p.Asp107His) variant of CASP3 (Caspase-3)
D107H (p.Asp107His) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data and structural context.
D107H (p.Asp107His) variant details
- p.Asp107His
- gnomAD rs1326139353
- Missense
- Variant Prioritization Score for Impact Estimate 0.622
- REVEL 0.49
- CADD 28.10
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00091)
- Structural context available