D107E (p.Asp107Glu) variant of CASP3 (Caspase-3)
D107E (p.Asp107Glu) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
D107E (p.Asp107Glu) variant details
- p.Asp107Glu
- gnomAD 4-184631927-A-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.34
- CADD 23.60
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available