C116R (p.Cys116Arg) variant of CASP3 (Caspase-3)
C116R (p.Cys116Arg) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.70 / 1. The record also includes population frequency data and structural context.
C116R (p.Cys116Arg) variant details
- p.Cys116Arg
- ExAC rs778409347
- Missense
- Variant Prioritization Score for Impact Estimate 0.7
- REVEL 0.73
- CADD 27.80
- PolyPhen-2 1.00
- SIFT 0.00
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available