A71V (p.Ala71Val) variant of CASP3 (Caspase-3)
A71V (p.Ala71Val) in CASP3 (Caspase-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.48 / 1. The record also includes population frequency data and structural context.
A71V (p.Ala71Val) variant details
- p.Ala71Val
- gnomAD rs1306969965
- Missense
- Variant Prioritization Score for Impact Estimate 0.479
- REVEL 0.32
- CADD 29.20
- PolyPhen-2 0.80
- SIFT 0.03
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available