Y36C (p.Tyr36Cys) variant of CARD11 (Q9BXL7)
Y36C (p.Tyr36Cys) in CARD11 (Q9BXL7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data and structural context.
Y36C (p.Tyr36Cys) variant details
- p.Tyr36Cys
- ExAC rs758661288
- gnomAD rs758661288
- Missense
- Variant Prioritization Score for Impact Estimate 0.315
- REVEL 0.16
- CADD 24.60
- PolyPhen-2 0.91
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available