Y11C (p.Tyr11Cys) variant of CARD11 (Q9BXL7)
Y11C (p.Tyr11Cys) in CARD11 (Q9BXL7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
Y11C (p.Tyr11Cys) variant details
- p.Tyr11Cys
- gnomAD rs1403650501
- Missense
- Variant Prioritization Score for Impact Estimate 0.107
- REVEL 0.04
- CADD 19.40
- PolyPhen-2 0.00
- SIFT 0.11
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available