S34N (p.Ser34Asn) variant of CARD11 (Q9BXL7)
S34N (p.Ser34Asn) in CARD11 (Q9BXL7) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
S34N (p.Ser34Asn) variant details
- p.Ser34Asn
- NCI-TCGA Cosmic COSV1007
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.373
- REVEL 0.10
- CADD 23.10
- PolyPhen-2 0.65
- SIFT 0.05
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available