R35H (p.Arg35His) variant of CARD11 (Q9BXL7)
R35H (p.Arg35His) in CARD11 (Q9BXL7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.51 / 1. The record also includes population frequency data and structural context.
R35H (p.Arg35His) variant details
- p.Arg35His
- Ensembl rs2115094164
- Missense
- Variant Prioritization Score for Impact Estimate 0.514
- REVEL 0.32
- CADD 27.20
- PolyPhen-2 0.88
- SIFT 0.00
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available