R114T (p.Arg114Thr) variant of CARD11 (Q9BXL7)
R114T (p.Arg114Thr) in CARD11 (Q9BXL7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.50 / 1. The record also includes population frequency data and structural context.
R114T (p.Arg114Thr) variant details
- p.Arg114Thr
- Ensembl rs2115090393
- Missense
- Variant Prioritization Score for Impact Estimate 0.499
- REVEL 0.31
- CADD 25.90
- PolyPhen-2 0.96
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available