L77S (p.Leu77Ser) variant of CARD11 (Q9BXL7)

L77S (p.Leu77Ser) in CARD11 (Q9BXL7) is a missense change. Clinical records from ClinVar, EBI, and UniProt describe it as uncertain significance in the context of BENTA disease; Severe combined immunodeficiency due to CARD11 deficiency. The record also includes structural context.

L77S (p.Leu77Ser) variant details