G3R (p.Gly3Arg) variant of CARD11 (Q9BXL7)
G3R (p.Gly3Arg) in CARD11 (Q9BXL7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
G3R (p.Gly3Arg) variant details
- p.Gly3Arg
- gnomAD rs1780842161
- Missense
- Variant Prioritization Score for Impact Estimate 0.409
- REVEL 0.11
- CADD 34.00
- PolyPhen-2 0.68
- SIFT 0.01
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available