G108R (p.Gly108Arg) variant of CARD11 (Q9BXL7)
G108R (p.Gly108Arg) in CARD11 (Q9BXL7) is a missense change. Clinical records from UniProt describe it as variant assessed as somatic; moderate impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.63 / 1. The record also includes population frequency data and structural context.
G108R (p.Gly108Arg) variant details
- p.Gly108Arg
- NCI-TCGA Cosmic COSV6271
- Ensembl rs2115090439
- Variant assessed as somatic; moderate impact.
- Missense
- Variant Prioritization Score for Impact Estimate 0.634
- REVEL 0.55
- CADD 26.80
- UniProt: Variant assessed as somatic; moderate impact.
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available