E121K (p.Glu121Lys) variant of CARD11 (Q9BXL7)
E121K (p.Glu121Lys) in CARD11 (Q9BXL7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
E121K (p.Glu121Lys) variant details
- p.Glu121Lys
- gnomAD rs1450598321
- Missense
- Variant Prioritization Score for Impact Estimate 0.374
- REVEL 0.10
- CADD 24.20
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available