D10E (p.Asp10Glu) variant of CARD11 (Q9BXL7)
D10E (p.Asp10Glu) in CARD11 (Q9BXL7) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
D10E (p.Asp10Glu) variant details
- p.Asp10Glu
- Ensembl rs2115094329
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.07
- CADD 21.10
- PolyPhen-2 0.00
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available