W33C (p.Trp33Cys) variant of CALR (Calreticulin)
W33C (p.Trp33Cys) in CALR (Calreticulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.66 / 1. The record also includes population frequency data, published literature, and structural context.
W33C (p.Trp33Cys) variant details
- p.Trp33Cys
- gnomAD 19-12939141-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.662
- REVEL 0.53
- CADD 33.00
- PolyPhen-2 0.88
- SIFT 0.00
- Population evidence available
- Structural context available
- Literature evidence available