K24R (p.Lys24Arg) variant of CALR (Calreticulin)
K24R (p.Lys24Arg) in CALR (Calreticulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
K24R (p.Lys24Arg) variant details
- p.Lys24Arg
- gnomAD rs1223633950
- Missense
- Variant Prioritization Score for Impact Estimate 0.294
- REVEL 0.07
- CADD 23.10
- PolyPhen-2 0.01
- SIFT 0.43
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available