G32E (p.Gly32Glu) variant of CALR (Calreticulin)
G32E (p.Gly32Glu) in CALR (Calreticulin) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
G32E (p.Gly32Glu) variant details
- p.Gly32Glu
- ESP rs140472880
- ExAC rs140472880
- TOPMed rs140472880
- gnomAD rs140472880
- Missense
- Variant Prioritization Score for Impact Estimate 0.323
- REVEL 0.02
- CADD 19.00
- PolyPhen-2 0.12
- SIFT 0.14
- Most common in the African/African-American population (allele frequency 3e-05)
- Structural context available